Aurantio-obtusin
Cat. No.：YN482406
| 产品名称: | Aurantio-obtusin |
| CAS No.: | 67979-25-3 |
| Chemical Name: | 1,3,7-trihydroxy-2,8-dimethoxy-6-methyl-9,10-anthracenedione |
| Synonyms: | 橙黄决明素 |
| 分子量: | 330.29 |
| 分子式: | C₁₇H₁₄O₇ |
| SMILES: | O=C1C2=C(C=C(C)C(O)=C2OC)C(C3=CC(O)=C(OC)C(O)=C13)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Aurantio-obtusin 是从决明子中分离出的一种蒽醌类化合物，具有抗炎、抗氧化、抗凝血、抗高血压的作用。在大鼠中，Aurantio-obtusin 通过内皮细胞 PI3K/AKT/ eNOS 依赖信号通路放松全身动脉，是一种潜在的新型血管扩张剂。Aurantio-obtusin 能抑制 IgE 介导的肥大细胞和过敏模型中的过敏反应，具有研究过敏相关疾病的潜力。 |
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Jang, D.S., Lee, G.Y., Kim, Y.S., et al.Anthraquinones from the seeds of Cassia tora with inhibitory activity on protein glycation and aldose reductaseBiol. Pharm. Bull.30(11),2207-2210(2007)
Amakura, Y., Yoshimura, M., Takaoka, M., et al.Characterization of natural aryl hydrocarbon receptor agonists from cassia seed and rosemaryMolecules19(4),4956-4966(2014)
Yun-Choi, H.S., Kim, J.H., and Takido, M.Potential inhibitors of platelet aggregation from plant sources, V. Anthraquinones from seeds of Cassia obtusifolia and related compoundsJ. Nat. Prod.53(3),630-633(1990)
Li, S., Li, Q., Lv, X., et al.Aurantio-obtusin relaxes systemic arteries through endothelial PI3K/AKT/eNOS-dependent signaling pathway in ratsJ. Pharmacol. Sci.128(3),108-115(2015)
Mbatchou, V.C., Tchouassi, D.P., Dickson, R.A., et al.Mosquito larvicidal activity of Cassia tora seed extract and its key anthraquinones aurantio-obtusin and obtusinParasit. Vectors10(1),562(2017)
