Aristolochic acid B
Cat. No.：YN482473
CAS No. ：475-80-9
| 产品名称: | Aristolochic acid B |
| CAS No.: | 475-80-9 |
| Chemical Name: | 6-nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid |
| Synonyms: | 马兜铃酸 B |
| 分子量: | 311.25 |
| 分子式: | C₁₆H₉NO₆ |
| SMILES: | O=C(C1=C2C([N+]([O-])=O)=CC3=CC=CC=C3C2=C(OCO4)C4=C1)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Aristolochic acid B 是马兜铃酸 (AA) 的主要成分之一，来自马兜铃科 (Aristolochiaceae) 分类群的天然产物。 已知马兜铃酸是有效的诱变剂和致癌物质。Aristolochic acid B 在体内表现出比 Aristolochic acid I 更大的致癌风险。 |
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Schmeiser, H.H., Schoepe, K.-B., and Wiessler, M.DNA adduct formation of aristolochic acid I and II in vitro and in vivoCarcinogenesis9(2),297-303(1988)
Yeh, Y.-H., Lee, Y.-T., Hsieh, H.-S., et al.Short-term toxicity of aristolochic acid, aristolochic acid-I and aristolochic acid-II in ratsFood Chem. Toxicol.46(3),1157-1163(2008)
