Escin IB
Cat. No.:YN482484
CAS No. :26339-90-2
产品名称: | Escin IB |
CAS No.: | 26339-90-2 |
Chemical Name: | (3β,4β,16α,21β,22α)-22-(acetyloxy)-16,23,28-trihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→4)]-β-D-glucopyranosiduronic acid |
Synonyms: | 七叶皂苷B |
分子量: | 1131.26 |
分子式: | C₅₅H₈₆O₂₄ |
SMILES: | OC[C@]1([C@H]2OC(C)=O)[C@](CC(C)(C)[C@H]2OC(/C(C)=C\C)=O)([H])C3=CC[C@@]4([H])[C@@](C)(CC[C@]5([H])[C@@]4(CC[C@H](O[C@@](O[C@H](C(O)=O)[C@@H](O[C@]([C@@H]([C@@H](O)[C@@H]6O)O)([H])O[C@@H]6CO)[C@@H]7O)([H])[C@@H]7O[C@]([C@@H]([C@@H](O)[C@@H]8O)O)([H])O[C@@ |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Escin IB 是一种从马栗子 (Aesculus hippocastanum) 种子的皮和胚乳中分离出的皂苷。Escin IB 对pancreatic lipase活性有抑制作用。 |
IC50和靶点: | |
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Yang, X.-W., Zhao, J., Cui, Y.-X., et al.Anti-HIV-1 protease triterpenoid saponins from the seeds of Aesculus chinensisJ. Nat. Prod.62(11),1510-1513(1999)
Matsuda, H., Li, Y., Murakami, T., et al.Effects of escins Ia, Ib, IIa, and IIb from horse chestnut, the seeds of Aesculus hippocastanum L., on acute inflammation in animalsBiol. Pharm. Bull.20(10),1092-1095(1997)
Yoshikawa, M., Harada, E., Murakami, T., et al.Escins-Ia, Ib, IIa, IIb, and IIIa, bioactive triterpene oligoglycosides from the seeds of Aesculus hippocastanum L.: Their inhibitory effects on ethanol absorption and hypoglycemic activity on glucose tolerance testChem. Pharm. Bull. (Tokyo)42(6),1357-1359(1994)
Matsuda, H., Li, Y., and Yoshikawa, M.Gastroprotections of escins Ia, Ib, IIa, and IIb on ethanol-induced gastric mucosal lesions in ratsEur. J. Pharmacol.373(1),63-70(1999)