Hecogenin
Cat. No.：YN482665
CAS No. ：467-55-0
| 产品名称: | Hecogenin |
| CAS No.: | 467-55-0 |
| Chemical Name: | (3β,5α,25R)-3-hydroxy-spirostan-12-one |
| Synonyms: | 海柯吉宁 |
| 分子量: | 430.62 |
| 分子式: | C₂₇H₄₂O₄ |
| SMILES: | [H][C@]1(O[C@@]2(OC[C@H](C)CC2)[C@@H](C)[C@@]1([C@]34C)[H])C[C@@]3([H])[C@]5([H])CC[C@@]6([H])C[C@@H](O)CC[C@]6(C)[C@@]5([H])CC4=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Hecogenin 是从龙舌兰 (Agave sisalana) 分离的类固醇皂苷，是人 UDP-葡萄糖醛酸糖基转移酶的选择性抑制剂。Hecogenin 具有广泛的药理活性，包括抗炎，抗真菌和胃保护作用。 |
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Cripps, A.L., and Blunden, G.A quantitative gas-liquid chromatographic method for the estimation of hecogenin and tigogenin in the leaves, juice and sapogenin concentrates of Agave sisalanaSteroids31(5),661-669(1978)
Tsai, P.L., Wang, J.P., Chang, C.W., et al.Constituents and bioactive principles of Polygonum chinensisPhytochemistry49(6),1663-1666(1998)
Santos Cerqueira, G., dos Santos e Silva, G., Rios Vasconcelos, E., et al.Effects of hecogenin and its possible mechanism of action on experimental models of gastric ulcer in miceEur. J. Pharmacol.683(1-3),260-269(2012)
Elsayed, H.E., Ebrahim, H.Y., Haggag, E.G., et al.Rationally designed hecogenin thiosemicarbazone analogs as novel MEK inhibitors for the control of breast malignanciesBioorg. Med. Chem.25(24),6297-6312(2017)
Vincent, A.M., Backus, C., Taubman, A.A., et al.Identification of candidate drugs for the treatment of ALSAmyotroph. Lateral Scler. Other Motor Neuron Disord.6(1),29-36(2005)
