Gymnemic acid I
Cat. No.:YN482947
CAS No. :122168-40-5
产品名称: | Gymnemic acid I |
CAS No.: | 122168-40-5 |
Chemical Name: | (3β,4α,16β,21β,22α)-28-(acetyloxy)-16,22,23-trihydroxy-21-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl-β-D-glucopyranosiduronic acid |
Synonyms: | (+)-Gymnemic acid I,Gymnemic acid I, (+)-,匙羹藤酸 I |
分子量: | 806.98 |
分子式: | C₄₃H₆₆O₁₄ |
SMILES: | O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1O[C@@H]2CC[C@]3(C)[C@@]4([H])CC=C5[C@]6([H])CC(C)(C)[C@H](OC(/C(C)=C/C)=O)[C@@H](O)[C@@](COC(C)=O)6[C@H](O)C[C@](C)5[C@@](C)4CC[C@]([H])3[C@@]2(C)CO |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Gymnemic acid I 是存在Gymnema sylvestre中的一种具有活性的三萜皂苷。Gymnemic acid I 能减少细胞在高糖应激下凋亡。 |
IC50和靶点: | |
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Wu, Y., Hu, Y., Yuan, Y., et al.Gymnemic acid I triggers mechanistic target of rapamycin-mediated β cells cytoprotection through the promotion of autophagy under high glucose stressJ. Cell. Physiol.234(6),9370-9377(2019)
Kinghorn, A.D., Chin, Y.-W., Pan, L., et al.Natural Products as Sweeteners and Sweetness ModifiersComprehensive Natural Products II,269-315(2010)