Cephalomannine
Cat. No.：YN290491
| 产品名称: | Cephalomannine |
| CAS No.: | 71610-00-9 |
| Chemical Name: | αR-hydroxy-βS-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]amino]-benzenepropanoic acid, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano- |
| Synonyms: | 三尖杉宁碱 |
| 分子量: | 831.90 |
| 分子式: | C₄₅H₅₃NO₁₄ |
| SMILES: | O=C(/C(C)=C/C)N[C@@H](C1=CC=CC=C1)[C@H](C(O[C@@H]2C(C)=C([C@@H](OC(C)=O)C([C@@]3(C)[C@]([C@](OC(C)=O)(CO4)[C@H]4C[C@@H]3O)([H])[C@@H]5OC(C6=CC=CC=C6)=O)=O)C(C)(C)[C@@]5(O)C2)=O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cephalomannine 是一种可以从大多数三尖杉属植物中分离得到的一种紫杉醇 (HY-B0015) 生物碱类似物。Cephalomannine 是一种具有口服活性的抗肿瘤试剂 (anti-tumor agent)，可作为化疗试剂用于癌症研究。 |
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Li, D., Fu, D., Zhang, Y., et al.Isolation, purification, and identification of taxol and related taxanes from taxol-producing fungus Aspergillus niger subsp. taxiJ. Microbiol. Biotechnol.27(8),1379-1385(2017)
Kobayashi, J., Hosoyama, H., Wang, X.-X., et al.Effects of taxoids from Taxus cuspidata on microtubule depolymerization and vincristine accumulation in MDR cellsBioorg. Med. Chem. Lett.7(4),393-398(1997)
