Cediranib maleate
Cat. No.：YN440247
CAS No. ：857036-77-2
规格
价格(RMB)
库存
| 产品名称: | Cediranib maleate |
| CAS No.: | 857036-77-2 |
| Chemical Name: | |
| Synonyms: | 西地尼布马来酸盐; AZD-2171 maleate |
| 分子量: | 566.58 |
| 分子式: | C₂₉H₃₁FN₄O₇ |
| SMILES: | O=C(O)/C=C\C(O)=O.FC1=C(OC2=C(C(C=C3OCCCN4CCCC4)=NC=N2)C=C3OC)C=CC5=C1C=C(C)N5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cediranib maleate (AZD-2171 maleate) 是高选择性，有口服活性的VEGFR2抑制剂，对Flt1，KDR，Flt4，PDGFRα，PDGFRβ，c-Kit的IC50值分别为小于1， 小于3，5，5，36，2nM。 |
| IC50和靶点: | [{name:"Flt-1:5 nM (IC50)"},{name: "KDR:1 nM (IC50)"},{name: "Flt-4:3 nM (IC50)"},{name: "PDGFRα:36 nM (IC50)"},{name: "PDGFRβ:5 nM (IC50)"},{name: "c-Kit:2 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
