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8-Bromo-cAMP sodium salt

Cat. No.:YN440204

  • CAS No. :76939-46-3

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    • 产品名称: 8-Bromo-cAMP sodium salt
      CAS No.: 76939-46-3
      Chemical Name: 8-bromo-cyclic 3',5'-(hydrogen phosphate)-adenosine, monosodium salt
      Synonyms:8-Br-Camp sodium salt
      分子量:430.08
      分子式:C₁₀H₁₀BrN₅NaO₆P
      SMILES:BrC1=NC2=C(N=CN=C2N)N1[C@H](O[C@@](CO3)([H])[C@@]4([H])OP3(O[Na])=O)[C@@H]4O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) 是一种环 AMP 类似物,是一种环 AMP 依赖性蛋白激酶 (PKA) 激活剂。
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    • Sandberg, M., Butt, E., Nolte, C., et al.Characterization of Sp-5,6-dichloro-1-β-D-ribofuranosylbenzimidazole-3',5'-monophosphorothioate (Sp-5,6-DCl-cBiMPS) as a potent and specific activator of cyclic-AMP-dependent protein kinase in cell extracts and intact cellsBiochem. J.279(Pt 2),521-527(1991)

      Yokozaki, H., Tortora, G., Pepe, S., et al.Unhydrolyzable analogues of adenosine 3':5'-monophosphate demonstrating growth inhibition and differentiation in human cancer cellsCancer Res.52(9),2504-2508(1992)

      Minonishi, T., Ogawa, K., Tokinaga, Y., et al.Differential vasodilation response to olprinone in rabbit renal and common carotid arteriesJ. Anesth.24(1),61-66(2010)

      Andoh, T., and Kuraishi, Y.Antipruritic mechanisms of topical E6005, a phosphodiesterase 4 inhibitor: Inhibition of responses to proteinase-activated receptor 2 stimulation mediated by increase in intracellular cyclic AMPJ. Dermatol. Sci.76(3),206-213(2014)

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