PKA Inhibitor Fragment (6-22) amide
Cat. No.：YN440436
CAS No. ：121932-06-7
规格
价格(RMB)
库存
| 产品名称: | PKA Inhibitor Fragment (6-22) amide |
| CAS No.: | 121932-06-7 |
| Chemical Name: | L-threonyl-L-tyrosyl-L-alanyl-L-α-aspartyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-serylglycyl-L-arginyl-L-threonylglycyl-L-arginyl-L-arginyl-L-asparaginyl-L-alanyl-L-isoleucinamide |
| Synonyms: | PKI-(6-22)-amide |
| 分子量: | 1868.06 |
| 分子式: | C₈₀H₁₃₀N₂₈O₂₄ |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PKA Inhibitor Fragment (6-22) amide 是 cAMP 依赖性蛋白激酶A (PKA)的抑制剂，Ki值为 2.8 nM。PKA Inhibitor Fragment (6-22) amide 可显着逆转小鼠低水平的吗啡镇痛感受性。 |
| IC50和靶点: | [{name:"PKA:2.8 nM (Ki)"}] |
| In Vitro: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Glass, D.B., Cheng, H.C., Mende-Mueller, L., et al.Primary structural determinants essential for potent inhibition of cAMP-dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor proteinJ. Biol. Chem.264(15),8802-8810(1989)
Glass, D.B., Lundquist, L.J., Katz, B.M., et al.Protein kinase inhibitor-(6-22)-amide peptide analogs with standard and nonstandard amino acid substitutions for phenylalanine 10. Inhibition of cAMP-dependent protein kinaseJ. Biol. Chem.264(24),14579-14584(1989)
