GSK-872
Cat. No.：YN270037
CAS No. ：1346546-69-7
规格
价格(RMB)
库存
| 产品名称: | GSK-872 |
| CAS No.: | 1346546-69-7 |
| Chemical Name: | N-5-benzothiazolyl-6-[(1-methylethyl)sulfonyl]-4-quinolinamine |
| Synonyms: | GSK2399872A,GSK'872,GSK872 |
| 分子量: | 383.49 |
| 分子式: | C₁₉H₁₇N₃O₂S₂ |
| SMILES: | O=S(C1=CC=C2N=CC=C(NC3=CC=C(SC=N4)C4=C3)C2=C1)(C(C)C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GSK-872 是RIPK3抑制剂，高亲和力结合 RIP3 激酶结构域，IC50为1.8 nM，并抑制激酶活性，IC50为1.3 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Kaiser, W.J., Sridharan, H., Huang, C., et al.Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKLJ. Biol. Chem.288(43),31268-31279(2013)
