Necrostatin 2
Cat. No.：YN270286
CAS No. ：852391-19-6
| 产品名称: | Necrostatin 2 |
| CAS No.: | 852391-19-6 |
| Chemical Name: | 5R-[(7-chloro-1H-indol-3-yl)methyl]-3-methyl-2,4-imidazolidinedione |
| Synonyms: | Necrostatin 2; Necrostatin-2; Necrostatin2; Nec-2; Nec 2; Nec2; MTH-DL-Tryptophan, Necroptotic Inhibitor. |
| 分子量: | 277.71 |
| 分子式: | C₁₃H₁₂ClN₃O₂ |
| SMILES: | ClC1=C2C(C(C[C@@H]3C(N(C)C(N3)=O)=O)=CN2)=CC=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Necrostatin 2 是一种有效的程序性坏死 (necroptosis) 抑制剂。作用于TNF-α处理的FADD缺陷型Jurkat T细胞，抑制程序性坏死，EC50为 0.05 μM。Necrostatin 2 为RIPK1抑制剂。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Teng, X., Degterev, A., Jagtap, P., et al.Structure-activity relationship study of novel necroptosis inhibitorsBioorg. Med. Chem. Lett.15(22),5039-5044(2005)
