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Sparsentan

Cat. No.：254740-64-2

  • CAS No. ：254740-64-2

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    • 产品名称: Sparsentan
      CAS No.: 254740-64-2
      Chemical Name:
      Synonyms:RE-021; DARA-a
      分子量:592.75
      分子式:C₃₂H₄₀N₄O₅S
      SMILES:O=S(C1=CC=CC=C1C2=CC=C(CN3C(CCCC)=NC4(CCCC4)C3=O)C=C2COCC)(NC5=NOC(C)=C5C)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Murugesan, N., Gu, Z., Fadnis, L., et al.Dual angiotensin II and endothelin A receptor antagonists: Synthesis of 2'-substituted N-3-isoxazolyl biphenylsulfonamides with improved potency and pharmacokineticsJ. Med. Chem.48(1),171-179(2005)", 'Nagasawa, H., Suzuki, H., Jenkinson, C., et al.The dual endothelin ETA and angiotensin AT1 receptor blocker sparsentan protects against the development of albuminuria and glomerulosclerosis in the gddY mouse model of IgANephrol. Dial. Transplant.35(Suppl. 3),P0348(2020)
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