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SirReal2

Cat. No.：709002-46-0

  • CAS No. ：709002-46-0

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    • 产品名称: SirReal2
      CAS No.: 709002-46-0
      Chemical Name:
      Synonyms:
      分子量:420.55
      分子式:C₂₂H₂₀N₄OS₂
      SMILES:O=C(NC1=NC=C(CC2=C3C=CC=CC3=CC=C2)S1)CSC4=NC(C)=CC(C)=N4
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Tang, B.L., and Chua, C.E.L.SIRT2, tubulin deacetylation, and oligodendroglia differentiationCell Motil. Cytoskeleton65,179-182(2008)', 'North, B.J., Marshall, B.L., Borra, M.T., et al.The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylaseMol. Cell11,437-444(2003)', 'Dryden, S.C., Nahhas, F.A., Nowak, J.E., et al.Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycleMol. Cell. Biol.23(9),3173-3185(2003)', 'de Oliveira, R.M., Sarkander, J., Kazantsev, A.G., et al.SIRT2 as a therapeutic target for age-related disordersFront. Pharmacol.3,82(2012)', 'Rumpf, T., Schiedel, M., Karaman, B., et al.Selective Sirt2 inhibition by ligand-induced rearrangement of the active siteNat. Commun.6,(2015)
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