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Sirtuin modulator 1

Cat. No.：2070015-26-6

  • CAS No. ：2070015-26-6

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    • 产品名称: Sirtuin modulator 1
      CAS No.: 2070015-26-6
      Chemical Name:
      Synonyms:SRT3025 Hydrochloride
      分子量:606.20
      分子式:C₃₁H₃₂ClN₅O₂S₂
      SMILES:O=C(C1=C(CCCOC)SC(C2=CC=CC=C2)=N1)NC3=CC=CC=C3C4=NC5=C(N=CC(CN6CCCC6)=C5)S4.Cl[H]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Gurt, I., Artsi, H., Cohen-Kfir, E., et al.The Sirt1 activators SRT2183 and SRT3025 Inhibit RANKL-induced osteoclastogenesis in bone marrow-derived macrophages and down-regulate Sirt3 in Sirt1 null cellsPLoS One10(7),e0134391(2015)', 'Chini, C.C.S., Espindola-Netto, J.M., Mondal, G., et al.SIRT1-activating compounds (STAC) negatively regulate pancreatic cancer cell growth and viability through a SIRT1 lysosomal-dependent pathwayClin. Cancer Res.22(10),2496-2507(2015)', 'Miranda, M.X., van Tits, L.J., Lohmann, C., et al.The Sirt1 activator SRT3025 provides atheroprotection in Apoe-/- mice by reducing hepatic Pcsk9 secretion and enhancing Ldlr expressionEur. Heart J.36(1),51-59(2015)
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