SirReal2
Cat. No.：YN310018
CAS No. ：709002-46-0
| 产品名称: | SirReal2 |
| CAS No.: | 709002-46-0 |
| Chemical Name: | 2-[(4,6-dimethyl-2-pyrimidinyl)thio]-N-[5-(1-naphthalenylmethyl)-2-thiazolyl]-acetamide |
| Synonyms: | |
| 分子量: | 420.55 |
| 分子式: | C₂₂H₂₀N₄OS₂ |
| SMILES: | O=C(NC1=NC=C(CC2=C3C=CC=CC3=CC=C2)S1)CSC4=NC(C)=CC(C)=N4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SirReal2 是一种有效的、同型选择性Sirt2抑制剂，IC50值为 140 nM，对 Sirt3-5 的活性影响很小。SirReal2 导致 HeLa 细胞中微管蛋白的高乙酰化，并导致检查点蛋白 BubR1 的失稳。 |
| IC50和靶点: | [{name:"SIRT2:140 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
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