SIRT7 inhibitor 97491
Cat. No.：YN310225
CAS No. ：1807758-81-1
| 产品名称: | SIRT7 inhibitor 97491 |
| CAS No.: | 1807758-81-1 |
| Chemical Name: | |
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| 分子量: | 285.73 |
| 分子式: | C₁₅H₁₂ClN₃O |
| SMILES: | NC1=CC(NC2=NC=C(C3=CC=C(Cl)C=C3)O2)=CC=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SIRT7 inhibitor 97491 是一种有效的SIRT7抑制剂，IC50为 325 nM，SIRT7 inhibitor 97491 降低 SIRT7 去乙酰化酶活性，这种作用存在剂量依赖性。SIRT7 inhibitor 97491 通过在 K373/382 处进行乙酰化来提高 p53 的稳定性，从而防止肿瘤进展。SIRT7 inhibitor 97491 通过 caspase 途径促进凋亡 (apoptosis)。 |
| IC50和靶点: | [{name:"SIRT7:325 nM (IC50)"}] |
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| Solvent & Solubility: |
