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Amonafide

Cat. No.：69408-81-7

  • CAS No. ：69408-81-7

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    • 产品名称: Amonafide
      CAS No.: 69408-81-7
      Chemical Name:
      Synonyms:氨萘非特; AS1413
      分子量:283.33
      分子式:C₁₆H₁₇N₃O₂
      SMILES:O=C1N(C(C2=CC(N)=CC3=CC=CC1=C23)=O)CCN(C)C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Hsiang, Y.H., Jiang, J.B., and Liu, L.F.Topoisomerase II-mediated DNA cleavage by amonafide and its structural analogsMol. Pharmacol.36(3),371-376(1989)', 'Chen, Z., Liang, X., Zhang, H., et al.A new class of naphthalimide-based antitumor agents that inhibit topoisomerase II and induce lysosomal membrane permeabilization and apoptosisJ. Med. Chem.53(6),2589-2600(2010)', 'Liu, Y., Norton, J.T., Witschi, M.A., et al.Methoxyethylamino-numonafide is an efficacious and minimally toxic amonafide derivative in murine models of human cancerNeoplasia13(5),453-460(2011)', 'Li, M., Wang, Y., Ge, C., et al.Synthesis and biological evaluation of novel alkylated polyamine analogues as potential anticancer agentsEur. J. Med. Chem.143,1732-1743(2018)
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