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NVP-BAW2881

Cat. No.:YN440010

  • CAS No. :861875-60-7

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    • 产品名称: NVP-BAW2881
      CAS No.: 861875-60-7
      Chemical Name: 6-[(2-amino-4-pyrimidinyl)oxy]-N-[3-(trifluoromethyl)phenyl]-1-naphthalenecarboxamide
      Synonyms:BAW2881
      分子量:424.38
      分子式:C₂₂H₁₅F₃N₄O₂
      SMILES:O=C(C1=C2C=CC(OC3=NC(N)=NC=C3)=CC2=CC=C1)NC4=CC=CC(C(F)(F)F)=C4
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: NVP-BAW2881 (BAW2881) 是有效,选择性的VEGFR2抑制剂,IC50为值9 nM。
      IC50和靶点: [{name:"VEGFR1:820 nM (IC50)"},{name: "VEGFR2:9 nM (IC50)"},{name: "VEGFR3:420 nM (IC50)"},{name: "Tie2:650 nM (IC50)"}]
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    • Halin, C., Fahrngruber, H., Meingassner, J.G., et al.Inhibition of chronic and acute skin inflammation by treatment with a vascular endothelial growth factor receptor tyrosine kinase inhibitorAm. J. Pathol.173(1),265-277(2008)

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