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SU5408

Cat. No.:YN440074

  • CAS No. :15966-93-5

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    • 产品名称: SU5408
      CAS No.: 15966-93-5
      Chemical Name: 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid, ethyl ester
      Synonyms:VEGFR2 Kinase Inhibitor I
      分子量:310.35
      分子式:C₁₈H₁₈N₂O₃
      SMILES:O=C(C1=C(C)NC(/C=C2C(NC3=C\2C=CC=C3)=O)=C1C)OCC
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: SU5408 (VEGFR2 Kinase Inhibitor I) 是有效的,可渗透细胞的VEGFR2激酶抑制剂,IC50值为 70 nM。
      IC50和靶点: [{name:"VEGFR2:70 nM (IC50)"}]
      In Vitro:
      In Vivo:
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    • Sun, L., Tran, N., Tang, F., et al.Synthesis and biological evaluations of 3-substituted indolin-2-ones: A novel class of tyrosine kinase inhibitors that exhibit selectivity toward particular receptor tyrosine kinasesJ. Med. Chem.41(14),2588-2603(1998)

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