SU5408
Cat. No.:YN440074
| 产品名称: | SU5408 |
| CAS No.: | 15966-93-5 |
| Chemical Name: | 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid, ethyl ester |
| Synonyms: | VEGFR2 Kinase Inhibitor I |
| 分子量: | 310.35 |
| 分子式: | C₁₈H₁₈N₂O₃ |
| SMILES: | O=C(C1=C(C)NC(/C=C2C(NC3=C\2C=CC=C3)=O)=C1C)OCC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SU5408 (VEGFR2 Kinase Inhibitor I) 是有效的,可渗透细胞的VEGFR2激酶抑制剂,IC50值为 70 nM。 |
| IC50和靶点: | [{name:"VEGFR2:70 nM (IC50)"}] |
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| Solvent & Solubility: |
Sun, L., Tran, N., Tang, F., et al.Synthesis and biological evaluations of 3-substituted indolin-2-ones: A novel class of tyrosine kinase inhibitors that exhibit selectivity toward particular receptor tyrosine kinasesJ. Med. Chem.41(14),2588-2603(1998)