Hinokitiol
Cat. No.：YN410086
CAS No. ：499-44-5
| 产品名称: | Hinokitiol |
| CAS No.: | 499-44-5 |
| Chemical Name: | 2-hydroxy-4-(1-methylethyl)-2,4,6-cycloheptatrien-1-one |
| Synonyms: | 桧木醇; β-Thujaplicin |
| 分子量: | 164.20 |
| 分子式: | C₁₀H₁₂O₂ |
| SMILES: | O=C1C(O)=CC(C(C)C)=CC=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Hinokitiol 是从日本扁柏中分离到的挥发油成分，能够降低Nrf2的表达，减少DNMT1和 UHRF1 的 mRNA 和蛋白的表达，具有抗感染、抗氧化及抗肿瘤等活性。 |
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Anderson, A.B., and Gripenberg, J.Antibiotic substances from the heart wood of Thuja plicata D. Don; the constitution of β-thujaplicinActa. Chem. Scand.2(8),644-650(1948)
Komaki, N., Watanabe, T., Ogasawara, A., et al.Antifungal mechanism of hinokitiol against Candida albicansBiol. Pharm. Bull.31(4),735-737(2008)
Morita, Y., Sakagami, Y., Okabe, T., et al.The mechanism of the bactericidal activity of hinokitiolBiocontrol Sci.12(3),101-110(2007)
Lee, Y.S., Choi, K.M., Kim, W., et al.Hinokitiol inhibits cell growth through induction of S-phase arrest and apoptosis in human colon cancer cells and suppresses tumor growth in a mouse xenograft experimentJ. Nat. Prod.76(12),2195-2202(2013)
Lin, K.H., Kuo, J.R., Lu, W.J., et al.Hinokitiol inhibits platelet activation ex vivo and thrombus formation in vivoBiochem. Pharmacol.85(10),1478-1485(2013)
Suzuki, H., Ueda, T., Juránek, I., et al.Hinokitiol, a selective inhibitor of the platelet-type isozyme of arachidonate 12-lipoxygenaseBiochem. Bioph. Res. Commun.275(3),885-889(2000)
