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Kinsenoside

Cat. No.:YN410132

  • CAS No. :151870-74-5

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Kinsenoside
      CAS No.: 151870-74-5
      Chemical Name: 4R-(β-D-glucopyranosyloxy)dihydro-2(3H)-furanone
      Synonyms:金线莲苷
      分子量:264.23
      分子式:C₁₀H₁₆O₈
      SMILES:O=C1OC[C@H](O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Kinsenoside 是从金盏花属植物中分离得到的主要活性成分,具有多种生物活性和药理作用。Kinsenoside 以 Nrf2 依赖的方式保护髓核细胞 (NPCs) 在氧化应激下的生存能力,防止细胞凋亡、衰老和线粒体功能障碍。
      IC50和靶点:
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    • Du, X.-M., Sun, N.-Y., Irino, N., et al.Glycosidic constituents from in vitro Anoectochilus formosanusChem. Pharm. Bull. (Tokyo)48(11),1803-1804(2000)

      Cheng, K.T., Wang, Y.S., Chou, H.C., et al.Kinsenoside-mediated lipolysis through an AMPK-dependent pathway in C3H10T1/2 adipocytes: Roles of AMPK and PPARα in the lipolytic effect of kinsenosidePhytomedicine22(6),641-647(2015)

      Hsiao, H.-B., Hsieh, C.-C., Wu, J.-B., et al.Kinsenoside inhibits the inflammatory mediator release in a type-II collagen induced arthritis mouse model by regulating the T cells responsesBMC Complement. Altern. Med.16,80(2016)

      Xiang, M., Liu, T., Tan, W., et al.Effects of kinsenoside, a potential immunosuppressive drug for autoimmune hepatitis, on dendritic cells/CD8+ T cells communication in miceHepatology64(6),2135-2150(2016)

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