CGK733
Cat. No.：YN420218
CAS No. ：905973-89-9
规格
价格(RMB)
库存
| 产品名称: | CGK733 |
| CAS No.: | 905973-89-9 |
| Chemical Name: | α-phenyl-N-[2,2,2-trichloro-1-[[[(4-fluoro-3-nitrophenyl)amino]thioxomethyl]amino]ethyl]-benzeneacetamide |
| Synonyms: | CGK 733 |
| 分子量: | 555.84 |
| 分子式: | C₂₃H₁₈Cl₃FN₄O₃S |
| SMILES: | FC1=CC=C(NC(NC(C(Cl)(Cl)Cl)NC(C(C2=CC=CC=C2)C3=CC=CC=C3)=O)=S)C=C1[N+]([O-])=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CGK733 是一种有效的ATM/ATR抑制剂，用于癌症研究。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Won, J., Kim, M., Kim, N., et al.Small molecule-based reversible reprogramming of cellular lifespanNat. Chem. Biol.2(7),369-374(2006)
Won, J., Kim, M., Kim, N., et al.Retraction: Small molecule-based reversible reprogramming of cellular lifespanNat. Chem. Biol.4(7),431(2008)
Williams, T.M., Nyati, S., Ross, B.D., et al.Molecular imaging of the ATM kinase activityInt. J. Radiat. Oncol. Biol. Phys.86(5),969-977(2013)
Choi, S., Toledo, L.I., Fernandez-Capetillo, O., et al.CGK733 does not inhibit ATM or ATR kinase activity in H460 human lung cancer cellsDNA Repair (Amst)10(10),1000-1001(2011)
Wang, M., Liu, G., Shan, G.-P., et al.In vivo and in vitro effects of ATM/ATR signaling pathway on proliferation, apoptosis, and radiosensitivity of nasopharyngeal carcinoma cellsCancer Biother. Radiopharm.32(6),193-203(2017)
