GR79236
Cat. No.：YN1710029
CAS No. ：124555-18-6
规格
价格(RMB)
库存
| 产品名称: | GR79236 |
| CAS No.: | 124555-18-6 |
| Chemical Name: | N-[(1S,2S)-2-hydroxycyclopentyl]-adenosine |
| Synonyms: | GR 79236 |
| 分子量: | 351.36 |
| 分子式: | C₁₅H₂₁N₅O₅ |
| SMILES: | OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C2N=CN=C3N[C@@H]4[C@@H](O)CCC4)O1)O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GR79236 是一种高效，选择性和具有口服活性的腺苷 A1 受体 (adenosine A1 receptor) 激动剂，对于A1和 A2 受体的Ki值分别为 3.1 nM 和 1300 nM。GR79236 具有抗伤害和抗炎作用。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Knutsen, L.J.S., Lau, J., Petersen, H., et al.N-Substituted adenosines as novel neuroprotective A1 agonists with diminished hypotensive effectsJ. Med. Chem.42,3463-3477(1999)
Merkel, L.A., Hawkins, E.D., Colussi, D.J., et al.Cardiovascular and antilipolytic effects of the adenosine agonist GR79236Pharmacology51(4),224-236(1995)
