N6-Cyclopentyladenosine
Cat. No.：YN1730017
CAS No. ：41552-82-3
| 产品名称: | N6-Cyclopentyladenosine |
| CAS No.: | 41552-82-3 |
| Chemical Name: | N-cyclopentyl-adenosine |
| Synonyms: | CPA; UK-80882 |
| 分子量: | 335.36 |
| 分子式: | C₁₅H₂₁N₅O₄ |
| SMILES: | OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C2N=CN=C3NC4CCCC4)O1)O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | N6-Cyclopentyladenosine (CPA) 是一个选择性的腺苷A1 受体 (Adenosine A1receptor)的激动剂，其对人A1、A2A和 A3受体的Ki分别为 2.3 nM、790 nM 和 43 nM。 |
| IC50和靶点: | |
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Klotz, K.-N.Adenosine receptors and their ligandsNaunyn-Schmiedeberg's Arch. Pharmacol.362(4),382-391(2000)
Klotz, K.-N., Hessling, J., Hegler, J., et al.Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cellsNaunyn-Schmiedeberg's Arch. Pharmacol.357(1),1-9(1998)
Barraco, R.A., el-Ridi, M.R., Ergene, E., et al.Adenosine receptor subtypes in the brainstem mediate distinct cardiovascular response patternsBrain Res. Bull.26(1),59-84(1991)
Gong, Q.-J., Li, Y.-Y., Xin, W.-J., et al.Differential effects of adenosine A1 receptor on pain-related behavior in normal and nerve-injured ratsBrain Res.1361,23-30(2010)
Jaishree, J., Kumaresan, S., Sudha, S., et al.Individual and combined effects of N6-cyclopentyladenosine, flunarizine and diazepam on aminophylline-induced recurrent generalized seizures in micePol. J. Pharmacol.55(4),559-564(2003)
