Nitrobenzylthioinosine
Cat. No.：YN1730123
CAS No. ：38048-32-7
| 产品名称: | Nitrobenzylthioinosine |
| CAS No.: | 38048-32-7 |
| Chemical Name: | 6-S-[(4-nitrophenyl)methyl]-6-thio-inosine |
| Synonyms: | NBMPR |
| 分子量: | 419.41 |
| 分子式: | C₁₇H₁₇N₅O₆S |
| SMILES: | OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C(N=CN=C32)SCC4=CC=C([N+]([O-])=O)C=C4)O1)O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Nitrobenzylthioinosine 是一种ENT1转运蛋白抑制剂，以高亲和力与ENT1转运蛋白结合。Nitrobenzylthioinosine 是一种光亲和探针，用于追踪大脑中腺苷的摄取位点，并且可以穿过血脑屏障。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Aronow, B., Allen, K., Patrick, J., et al.Altered nucleoside transporters in mammalian cells selected for resistance to the physiological effects of inhibitors of nucleoside transportJ. Biol. Chem.260(10),6226-6233(1985)
Yao, S.Y.M., Ng, A.M.L., Muzyka, W.R., et al.Molecular cloning and functional characterization of nitrobenzylthioinosine (NBMPR)-sensitive (es) and NBMPR-insensitive (ei) equilibrative nucleoside transporter proteins (rENT1 and rENT2) from rat tissuesJ. Biol. Chem.272(45),28423-28430(1997)
