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Abemaciclib methanesulfonate

Cat. No.：1231930-82-7

  • CAS No. ：1231930-82-7

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    • 产品名称: Abemaciclib methanesulfonate
      CAS No.: 1231930-82-7
      Chemical Name:
      Synonyms:LY2835219 methanesulfonate
      分子量:602.70
      分子式:C₂₈H₃₆F₂N₈O₃S
      SMILES:CC(N1C2=CC(C3=NC(NC4=NC=C(CN5CCN(CC)CC5)C=C4)=NC=C3F)=CC(F)=C2N=C1C)C.CS(=O)(O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Dickson, M.A.Molecular pathways: CDK4 inhibitors for cancer therapyClin. Cancer Res.20(13),3379-3383(2014)', 'Gelbert, L.M., Cai, S., Lin, X., et al.Preclinical characterization of the CDK4/6 inhibitor LY2835219: In-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with gemcitabineInvest. New. Drugs32(5),825-837(2014)', 'Tate, S.C., Cai, S., Ajamie, R.T., et al.Semi-mechanistic pharmacokinetic/pharmacodynamic modeling of the antitumor activity of LY2835219, a new cyclin-dependent kinase 4/6 inhibitor, in mice bearing human tumor xenograftsClin. Cancer Res.20(14),3763-3774(2014)
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