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NU2058

Cat. No.：161058-83-9

  • CAS No. ：161058-83-9

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    • 产品名称: NU2058
      CAS No.: 161058-83-9
      Chemical Name:
      Synonyms:O6-(Cyclohexylmethyl)guanine
      分子量:247.30
      分子式:C₁₂H₁₇N₅O
      SMILES:NC1=NC(OCC2CCCCC2)=C3NC=NC3=N1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Hardcastle, I.R., Arris, C.E., Bentley, J., et al.N2-substituted O6-cyclohexylmethylguanine derivatives: Potent inhibitors of cyclin-dependent kinases 1 and 2J. Med. Chem.47(15),3710-3722(2004)', 'Sayle, K.L., Bentley, J., Boyle, F.T., et al.Structure-based design of 2-arylamino-4-cyclohexylmethyl-5-nitroso-6-aminopyrimidine inhibitors of cyclin-dependent kinases 1 and 2Bioorg. Med. Chem. Lett.13(18),3079-3082(2003)', 'Johnson, N., Bentley, J., Wang, L.-Z., et al.Pre-clinical evaluation of cyclin-dependent kinase 2 and 1 inhibition in anti-estrogen-sensitive and resistant breast cancer cellsBr. J. Cancer102(2),342-350(2010)', 'Rigas, A.C., Robson, C.N., and Curtin, N.J.Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancerOncogene26(55),7611-7619(2007)
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