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Palbociclib hydrochloride

Cat. No.：827022-32-2

  • CAS No. ：827022-32-2

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    • 产品名称: Palbociclib hydrochloride
      CAS No.: 827022-32-2
      Chemical Name:
      Synonyms:PD 0332991 hydrochloride
      分子量:483.99
      分子式:C₂₄H₃₀ClN₇O₂
      SMILES:O=C1C(C(C)=O)=C(C)C2=CN=C(NC3=NC=C(N4CCNCC4)C=C3)N=C2N1C5CCCC5.Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Fry, D.W., Harvey, P.J., Keller, P.R., et al.Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenograftsMol. Cancer Ther.3(11),1427-1438(2004)', 'Finn, R.S., Dering, J., Conklin, D., et al.PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitroBreast Cancer Res.11(5),1-13(2009)', 'Lee, Y., Dominy, J.E., Choi, Y.J., et al.Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progressionNature510(7506),547-551(2014)
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