Evocalcet
Cat. No.：YN321168
CAS No. ：870964-67-3
| 产品名称: | Evocalcet |
| CAS No.: | 870964-67-3 |
| Chemical Name: | 4-[(3S)-3-[[(1R)-1-(1-naphthalenyl)ethyl]amino]-1-pyrrolidinyl]-benzeneacetic acid |
| Synonyms: | KHK7580 |
| 分子量: | 374.48 |
| 分子式: | C₂₄H₂₆N₂O₂ |
| SMILES: | O=C(O)CC1=CC=C(N2C[C@@H](N[C@@H](C3=C4C=CC=CC4=CC=C3)C)CC2)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Evocalcet 对钙敏感受体 (CaSR) 具有激活作用来自专利 WO 2017061621 A1，化合物 A。 |
| IC50和靶点: | |
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Kawata, T., Tokunaga, S., Murai, M., et al.A novel calcimimetic agent, evocalcet (MT4580/KHK7580), suppresses the parathyroid cell function with little effect on the gastrointestinal tract or CYP isozymes in vivo and in vitroPLoS One13(4),e0195316(2018)
