Ligustroflavone
Cat. No.：YN321722
CAS No. ：260413-62-5
| 产品名称: | Ligustroflavone |
| CAS No.: | 260413-62-5 |
| Chemical Name: | 7-[(O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→6)]-β-D-glucopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| Synonyms: | 女贞苷; Nuezhenoside |
| 分子量: | 724.66 |
| 分子式: | C₃₃H₄₀O₁₈ |
| SMILES: | O=C(C=C(C1=CC=C(O)C=C1)OC2=CC(O[C@H](O[C@H](CO[C@H](O[C@@H](C)[C@H](O)[C@H]3O)[C@@H]3O)[C@@H](O)[C@@H]4O)[C@@H]4O[C@@](O[C@@H](C)[C@H](O)[C@H]5O)([H])[C@@H]5O)=C6)C2=C6O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ligustroflavone 可从Ligustrum lucidum中提取得到，是一种潜在的钙敏感受体(CaSR)拮抗剂。Ligustroflavone对糖尿病性骨质疏松症小鼠有保护作用。 |
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Pieroni, A., and Pachaly, P.Isolation and structure elucidation of ligustroflavone, a new apigenin triglycoside from the leaves of Ligustrum vulgare L.Pharmazie55(1),78-80(2000)
Feng, R., Ding, F., Mi, X.-H., et al.Protective effects of ligustroflavone, an active compound from Ligustrum lucidum, on diabetes-induced osteoporosis in mice: A potential candidate as calcium-sensing receptor antagonistAm. J. Chin. Med.47(2),457-476(2019)
Zhang, Y.-Y., Liu, W.-N., Li, Y.-Q., et al.Ligustroflavone reduces necroptosis in rat brain after ischemic stroke through targeting RIPK1/RIPK3/MLKL pathwayNaunyn Schmiedebergs Arch. Pharmacol.392(9),1085-1095(2019)
