NPPB
Cat. No.：YN360064
CAS No. ：107254-86-4
| 产品名称: | NPPB |
| CAS No.: | 107254-86-4 |
| Chemical Name: | 5-nitro-2-[(3-phenylpropyl)amino]-benzoic acid |
| Synonyms: | NPPB |
| 分子量: | 300.31 |
| 分子式: | C₁₆H₁₆N₂O₄ |
| SMILES: | O=C(O)C1=CC([N+]([O-])=O)=CC=C1NCCCC2=CC=CC=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | NPPB 是外向整流氯化物通道 (ORCC) 的阻断剂。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Keeling, D.J., Taylor, A.G., and Smith, P.L.Effects of NPPB (5-nitro-2-(3-phenylpropylamino)benzoic acid) on chloride transport in intestinal tissues and the T84 cell lineBiochim. Biophys. Acta1115(1),42-48(1991)
Bertollini, C., Murana, E., Mosca, L., et al.Transient increase in neuronal chloride concentration by neuroactive aminoacids released from glioma cellsFront. Mol. Neurosci.5,100(2012)
Taniguchi, Y., Tonai-Kachi, H., and Shinjo, K.5-Nitro-2-(3-phenylpropylamino)benzoic acid is a GPR35 agonistPharmacology82(4),245-259(2008)
Lukacs, G.L., Nanda, A., Rotstein, O.D., et al.The chloride channel blocker 5-nitro-2-(3-phenylpropyl-amino) benzoic acid (NPPB) uncouples mitochondria and increases the proton permeability of the plasma membrane in phagocytic cellsFEBS Lett.288(1-2),17-20(1991)
