Lubiprostone
Cat. No.：YN360826
CAS No. ：136790-76-6
| 产品名称: | Lubiprostone |
| CAS No.: | 136790-76-6 |
| Chemical Name: | 16,16-difluoro-11α-hydroxy-9,15-dioxo-prostan-1-oic acid |
| Synonyms: | 鲁比前列酮; RU-0211; SPI-0211 |
| 分子量: | 390.46 |
| 分子式: | C₂₀H₃₂F₂O₅ |
| SMILES: | O=C(C(F)(F)CCCC)CC[C@@H]([C@@H](C1)O)[C@H](C1=O)CCCCCCC(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lubiprostone(SPI-0211;RU0211)是胃肠制剂，可作用于慢性便秘。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Lacy, B.E., and Levy, L.C.Lubiprostone: A chloride channel activatorJ. Clin. Gastroenterol.41(4),345-351(2007)
Cuppoletti, J., Malinowska, D.H., Tewari, K.P., et al.SPI-0211 activates T84 cell chloride transport and recombinant human ClC-2 chloride currentsAm. J. Physiol. Cell Physiol.287,C1173-C1183(2004)
Song, J., Yin, J., Xu, X., et al.Prokinetic effects of large-dose lubiprostone on gastrointestinal transit in dogs and its mechanismsAm. J. Transl. Res.7(3),513-521(2015)
