Satraplatin
Cat. No.：YN290423
CAS No. ：129580-63-8
| 产品名称: | Satraplatin |
| CAS No.: | 129580-63-8 |
| Chemical Name: | (OC-6-43)-bis(acetato-κO)amminedichloro(cyclohexanamine)-platinum |
| Synonyms: | 沙铂; BMS182751; BMY45594; JM216 |
| 分子量: | 500.28 |
| 分子式: | C₁₀H₂₂Cl₂N₂O₄Pt |
| SMILES: | [Cl-][Pt+4]([O-]C(C)=O)([O-]C(C)=O)([Cl-])([NH3])[NH2]C1CCCCC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Satraplatin 是一种烷化剂 (alkylator)，具有抗肿瘤效果。 |
| IC50和靶点: | |
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Kelland, L.R., Abel, G., McKeage, M.J., et al.Preclinical antitumor evaluation of bis-acetato-ammine-dichloro-cyclohexylamine platinum(IV): An orally active platinum drugCancer Res.53(11),2581-2586(1993)
McKeage, M.J., Boxall, F.E., Jones, M., et al.Lack of neurotoxicity of oral bisacetatoamminedichlorocyclohexylamine-platinum(IV) in comparison to cisplatin and tetraplatin in the ratCancer Res.54(3),629-631(1994)
Bhargava, A., and Vaishampayan, U.N.Satraplatin: Leading the new generation of oral platinum agentsExpert. Opin. Investig. Drugs18(11),1787-1797(2009)
