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Altretamine

Cat. No.:YN290501

  • CAS No. :645-05-6

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    • 参考文献
    • 产品名称: Altretamine
      CAS No.: 645-05-6
      Chemical Name: N2,N2,N4,N4,N6,N6-hexamethyl-1,3,5-triazine-2,4,6-triamine
      Synonyms:六甲蜜胺; ENT-50852; RB-1515; WR-95704
      分子量:210.28
      分子式:C₉H₁₈N₆
      SMILES:CN(C)C1=NC(N(C)C)=NC(N(C)C)=N1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Altretamine 是一种烷化剂 (alkylator),具有抗肿瘤活性。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Langdon, S.P., Simmonds, R.J., and Stevens, M.F.G.Triazines and related products. Part 26. Synthesis and chemistry of bicyclic analogues of the antitumour drug 2,4,6-tris(dimethylamino)-1,3,5-triazine (hexamethylmelamine)J. Chem. Soc. Perkin 1,993-998(1984)

      D'Incalci, M., Erba, E., Balconi, G., et al.Time dependence of the in vitro cytotoxicity of hexamethylmelamine and its metabolitesBr. J. Cancer41(4),630-635(1980)

      Miller, K.J., McGovern, R.M., and Ames, M.M.Effect of a hepatic activation system on the antiproliferative activity of hexamethylmelamine against human tumor cell linesCancer Chemother. Pharmacol.15(1),49-53(1985)

      Woo, J.H., Shimoni, Y., Yang, W.S., et al.Elucidating compound mechanism of action by network perturbation analysisCell162(2),441-451(2015)

      LaBrecque, G.C., Fye, R.L., DeMilo, A.B., et al.Substituted melamines as chemosterilants of house fliesJ. Econ. Entomol.61(6),1621-1632(1968)

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