NI-57
Cat. No.：YN310322
CAS No. ：1883548-89-7
| 产品名称: | NI-57 |
| CAS No.: | 1883548-89-7 |
| Chemical Name: | 4-cyano-N-(1,2-dihydro-1,3-dimethyl-2-oxo-6-quinolinyl)-2-methoxy-benzenesulfonamide |
| Synonyms: | NI57,NI 57 |
| 分子量: | 383.42 |
| 分子式: | C₁₉H₁₇N₃O₄S |
| SMILES: | COC1=CC(C#N)=CC=C1S(NC2=CC3=C(C=C2)N(C)C(C(C)=C3)=O)(=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | NI-57 为溴结构域和植物同源锌指结构域 (BRPF) 蛋白家族的抑制剂，对 BRPF1，BRPF2 (BRD1) 和 BRPF3 的IC50值分别为 3.1，46 和 140 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Ullah, M., Pelletier, N., Xiao, L., et al.Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexesMol. Cell Biol.28(22),6828-6843(2008)
Klein, B.J., Lalonde, M.E., Côté, J., et al.Crosstalk between epigenetic readers regulates the MOZ/MORF HAT complexesEpigenetics9(2),186-193(2014)
