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Pimelic Diphenylamide 106

Cat. No.：937039-45-7

  • CAS No. ：937039-45-7

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    • 产品名称: Pimelic Diphenylamide 106
      CAS No.: 937039-45-7
      Chemical Name:
      Synonyms:RGFA-8; TC-H 106; Histone Deacetylase Inhibitor VII
      分子量:339.43
      分子式:C₂₀H₂₅N₃O₂
      SMILES:O=C(NC1=CC=CC=C1N)CCCCCC(NC2=CC=C(C)C=C2)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Chou, C.J., Herman, D., and Gottesfeld, J.M.Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylasesJ. Biol. Chem.283(51),35402-35409(2008)', 'Rai, M., Soragni, E., Jenssen, K., et al.HDAC inhibitors correct frataxin deficiency in a Friedreich ataxia mouse modelPLoS One3(4),(2008)', "Herman, D., Jenssen, K., Burnett, R., et al.Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxiaNat. Chem. Biol.2(10),551-558(2006)", "Thomas, E.A., Coppola, G., Desplats, P.A., et al.The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic miceProc. Natl. Acad. Sci. USA105(40),15564-15569(2008)
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