Suberoyl bis-hydroxamic acid

Cat. No.：38937-66-5

CAS No. ：38937-66-5

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50mg

￥523

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100mg

￥903

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250mg

￥1805

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500mg

￥1805

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1 g

￥1805

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参考文献

产品名称:	Suberoyl bis-hydroxamic acid
CAS No.:	38937-66-5
Chemical Name:
Synonyms:	Suberohydroxamic acid; SBHA
分子量:	204.22
分子式:	C₈H₁₆N₂O₄
SMILES:	O=C(NO)CCCCCCC(NO)=O
存储:	Please store the product under the recommended conditions in theCertificate of Analysis.
运输:	Room temperature in continental US; may vary elsewhere.

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Purity: 0.98

Richon, V.M., Emiliani, S., Verdin, E., et al.A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylasesProc. Natl. Acad. Sci. USA95(6),3003-3007(1998)', 'Brinkmann, H., Dahler, A.L., Popa, C., et al.Histone hyperacetylation induced by histone deacetylase inhibitors is not sufficient to cause growth inhibition in human dermal fibroblastsJ. Biol. Chem.276(25),22491-22499(2001)', 'You, B.R., and Park, W.H.Suberoyl bishydroxamic acid inhibits the growth of A549 lung cancer cells via caspase-dependent apoptosisMol. Cell. Biochem.,(2010)', 'Ning, L., Greenblatt, D.Y., Kunnimalaiyaan, M., et al.Suberoyl bis-hydroxamic acid activates Notch-1 signaling and induces apoptosis in medullary thyroid carcinoma cellsOncologist13,98-104(2008)', 'Zhang, X.D., Gillespie, S.K., Borrow, J.M., et al.The histone deacetylase inhibitor suberic bishydroxamate regulates the expression of multiple apoptotic mediators and induces mitochondria-dependent apoptosis of melanoma cellsMol. Cancer Ther.3(4),425-435(2004)', 'Zhang, X.D., Gillespie, S.K., Borrow, J.M., et al.The histone deacetylase inhibitor suberic bishydroxamate: A potential sensitizer of melanoma to TNF-related apoptosis-inducing ligand (TRAIL) induced apoptosisBiochem. Pharmacol.66,1537-1545(2003)', 'Flis, S., Gnyszka, A., Flis, K., et al.MS275 enhances cytotoxicity induced by 5-fluorouracil in the colorectal cancer cellsEur. J. Pharmacol.627,26-32(2010)', 'Flis, S., Gnyszka, A., and Splawinski, J.HDAC inhibitors, MS275 and SBHA, enhances cytotoxicity induced by oxaliplatin in the colorectal cancer cell linesBiochem. Biophys. Res. Commun.387,336-341(2009)