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Apicidin

Cat. No.：183506-66-3

  • CAS No. ：183506-66-3

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    • 产品名称: Apicidin
      CAS No.: 183506-66-3
      Chemical Name:
      Synonyms:OSI 2040
      分子量:623.78
      分子式:C₃₄H₄₉N₅O₆
      SMILES:O=C(NC(C(N1[C@]2([H])CCCC1)=O)[C@@H](C)CC)[C@@H](NC([C@@H](NC2=O)CCCCCC(CC)=O)=O)CC3=CN(OC)C4=C3C=CC=C4
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Darkin-Rattray, S.J., Gurnett, A.M., Myers, R.W., et al.Apicidin: A novel antiprotozoal agent that inhibits parasite histone deacetylaseProc. Natl. Acad. Sci. USA93(23),13143-13147(1996)', 'Khan, N., Jeffers, M., Kumar, S., et al.Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitorsBiochem. J.409(2),581-589(2008)', 'Ueda, T., Takai, N., Nishida, M., et al.Apicidin, a novel histone deacetylase inhibitor, has profound anti-growth activity in human endometrial and ovarian cancer cellsInt. J. Mol. Med.19,301-308(2007)', 'Luo, B., Chen, J., Zhou, G.-F., et al.Apicidin attenuates memory deficits by reducing the Aβ load in APP/PS1 miceCNS Neurosci. Ther.(0)0,1-12(2023)
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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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