Tanzisertib
Cat. No.：YN350161
CAS No. ：899805-25-5
| 产品名称: | Tanzisertib |
| CAS No.: | 899805-25-5 |
| Chemical Name: | trans-4-[[9-[(3S)-tetrahydro-3-furanyl]-8-[(2,4,6-trifluorophenyl)amino]-9H-purin-2-yl]amino]-cyclohexanol |
| Synonyms: | CC-930 |
| 分子量: | 448.44 |
| 分子式: | C₂₁H₂₃F₃N₆O₂ |
| SMILES: | O[C@H]1CC[C@H](NC2=NC=C3N=C(NC4=C(F)C=C(F)C=C4F)N([C@@H]5COCC5)C3=N2)CC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tanzisertib (CC-930) 是有效的JNK1/2/3抑制剂，IC50分别为61/7/6 nM。 |
| IC50和靶点: | [{name:"JNK3:6 nM (IC50)"},{name: "JNK2:7 nM (IC50)"},{name: "JNK1:61 nM (IC50)"}] |
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| Solvent & Solubility: |
Krenitsky, V.P., Nadolny, L., Delgado, M., et al.Discovery of CC-930, an orally active anti-fibrotic JNK inhibitorBioorg. Med. Chem. Lett.22(3),1433-1438(2012)
