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FTY720 (S)-Phosphate

Cat. No.：402616-26-6

  • CAS No. ：402616-26-6

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    • 产品名称: FTY720 (S)-Phosphate
      CAS No.: 402616-26-6
      Chemical Name:
      Synonyms:(S)-FTY720P; (S)-FTY720 phosphate
      分子量:387.45
      分子式:C₁₉H₃₄NO₅P
      SMILES:OC[C@](CCC1=CC=C(CCCCCCCC)C=C1)(N)COP(O)(O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Brinkmann, V., Pinschewer, D.D., Feng, L., et al.FTY720: Altered lymphocyte traffic results in allograft protectionTransplantation72(5),764-769(2001)', 'Brinkmann, V., Davis, M.D., Heise, C.E., et al.The immune modulator FTY720 targets sphingosine 1-phosphate receptorsJ. Biol. Chem.277(24),21453-21457(2002)', 'Albert, R., Hinterding, K., Brinkmann, V., et al.Novel immunomodulator FTY720 is phosphorylated in rats and humans to form a single stereoisomer. Identification, chemical proof, and biological characterization of the biologically active species and its enantiomerJ. Med. Chem.48(16),5373-5377(2005)', 'Kiuchi, M., Adachi, K., Tomatsu, A., et al.Asymmetric synthesis and biological evaluation of the enantiomeric isomers of the immunosuppressive FTY720-phosphateBioorg. Med. Chem.13(2),425-432(2005)', 'Brinkmann, V.FTY720: Mechanism of action and potential benefit in organ transplantationYonsei Med. J.45(6),991-997(2004)', 'Honig, S.M., Fu, S., Mao, X., et al.FTY720 stimulates multidrug transporter- and cysteinyl leukotriene-dependent T cell chemotaxis to lymph nodesJ. Clin. Invest.111(5),627-637(2003)', 'Payne, S.G., Oskeritizian, C.A., Griffiths, R., et al.The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptorsBlood109(3),1077-1085(2007)
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