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Siponimod

Cat. No.：1230487-00-9

  • CAS No. ：1230487-00-9

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    • 产品名称: Siponimod
      CAS No.: 1230487-00-9
      Chemical Name:
      Synonyms:BAF-312
      分子量:516.60
      分子式:C₂₉H₃₅F₃N₂O₃
      SMILES:O=C(C1CN(CC2=CC=C(/C(C)=N/OCC3=CC=C(C4CCCCC4)C(C(F)(F)F)=C3)C=C2CC)C1)O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Gergely, P., Nuesslein-Hildesheim, B., Guerini, D., et al.The selective sphingosine 1-phosphate receptor modulator BAF312 redirects lymphocyte distribution and has species-specific effects on heart rateBr. J. Pharmacol.167(5),1035-1047(2012)', 'Pan, S., Gray, N.S., Gai, W., et al.Discovery of BAF312 (siponimod), a potent and selective S1P receptor modulatorACS Med. Chem. Lett.4(3),333-337(2013)', "O'Sullivan, C., Schubart, A., Mir, A.K., et al.The dual S1PR1/S1PR5 drug BAF312 (siponimod) attenuates demyelination in organotypic slice culturesJ. Neuroinflammation13,31(2016)", 'Poirier, B., Briand, V., Kadereit, D., et al.A G protein-biased S1P1 agonist, SAR247799, protects endothelial cells without affecting lymphocyte numbersSci. Signal.13(634),eaax8050(2020)
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