Kevetrin hydrochloride
Cat. No.：YN270338
CAS No. ：66592-89-0
规格
价格(RMB)
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| 产品名称: | Kevetrin hydrochloride |
| CAS No.: | 66592-89-0 |
| Chemical Name: | carbamimidothioic acid, 3-cyanopropyl ester, monohydrochloride |
| Synonyms: | 4-Isothioureidobutyronitrile hydrochloride; thioureidobutyronitrile hydrochloride; thioureido butyronitrile hydrochloride |
| 分子量: | 179.67 |
| 分子式: | C₅H₁₀ClN₃S |
| SMILES: | NC(SCCCC#N)=N.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Kevetrin盐酸盐是一种肿瘤抑制蛋白p53的激动剂, 具有潜在的抗肿瘤活性。 |
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Kumar, A., Hiran, T., Holden, S.A., et al.Abstract 4470: KevetrinTM, a novel small molecule, activates p53, enhances expression of p21, induces cell cycle arrest and apoptosis in a human cancer cell lineCancer Res.71(8 Supp),4470(2011)
Kumar, A., Holden, S.A., Chafai-Fadela, K., et al.Abstract 2874: Kevetrin targets both MDM2-p53 and Rb-E2F pathways in tumor suppressionCancer Res.72(8 Supp),2874(2012)
Menon, K.Nitrile derivatives and their pharmaceutical use and compositions,(2012)
