NSC319726
Cat. No.：YN270372
CAS No. ：71555-25-4
| 产品名称: | NSC319726 |
| CAS No.: | 71555-25-4 |
| Chemical Name: | 2-[1-(2-pyridinyl)ethylidene]hydrazide, 1-azetidinecarbothioic acid |
| Synonyms: | ZMC1 |
| 分子量: | 234.32 |
| 分子式: | C₁₁H₁₄N₄S |
| SMILES: | C/C(C1=NC=CC=C1)=N\NC(N2CCC2)=S |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | NSC319726 (ZMC1) 是突变型p53R175再活化剂，能抑制表达p53R175的成纤维细胞增殖，IC50值为8nM，对野生型p53细胞无抑制作用。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Yu, X., Vazquez, A., Levine, A.J., et al.Allele-specific p53 mutant reactivationCancer Cell21(5),614-625(2012)
Sun, N., Li, D., Zhang, Y., et al.Repurposing an inhibitor of ribosomal biogenesis with broad anti-fungal activitySci. Rep.7(1),17014(2017)
