APS-2-79
Cat. No.：YN350009
CAS No. ：2002381-25-9
| 产品名称: | APS-2-79 |
| CAS No.: | 2002381-25-9 |
| Chemical Name: | |
| Synonyms: | APS-2-79;APS 2-79;6,7-dimethoxy-N-(2-methyl-4-phenoxyphenyl)quinazolin-4-amine;6,7-Dimethoxy-~{n}-(2-Methyl-4-Phenoxy-Phenyl)quinazolin-4-Amine;BDBM429286;BCP24938;US10548897, Compound 21;Q27456559;COC=1C=C2C(=NC=NC2=CC=1OC)NC1=C(C=C(C=C1)OC1=CC=CC=C1)C;6 |
| 分子量: | 387.43 |
| 分子式: | C₂₃H₂₁N₃O₃ |
| SMILES: | CC1=CC(OC2=CC=CC=C2)=CC=C1NC3=NC=NC4=CC(OC)=C(OC)C=C43 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | APS-2-79 是一种 Ras 激酶抑制子 (KSR) 依赖性的 RAF 介导的MEK磷酸化拮抗剂。APS-2-79 与 KSR2-MEK1 复合物内的KSR2直接结合，IC50为 120±23 nM。 |
| IC50和靶点: | [{name:"KSR2:120 nM (IC50)'}, 'MEK1'] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
