Hispidin
Cat. No.：YN310019
CAS No. ：555-55-5
| 产品名称: | Hispidin |
| CAS No.: | 555-55-5 |
| Chemical Name: | 6-[(1E)-2-(3,4-dihydroxyphenyl)ethenyl]-4-hydroxy-2H-pyran-2-one |
| Synonyms: | 6-[(1E)-2-(3,4-二羟基苯基)乙烯基]-4-羟基-2H-吡喃-2-酮 |
| 分子量: | 246.22 |
| 分子式: | C₁₃H₁₀O₅ |
| SMILES: | O=C1C=C(O)C=C(/C=C/C2=CC=C(O)C(O)=C2)O1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Hispidin 是一种PKC抑制剂，是一种产自Phellinus linteus的酚类化合物，具有很强的抗氧化、抗癌、抗糖尿病和抗痴呆作用。 |
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Nambudiri, A.M., Vance, C.P., and Towers, G.H.Effect of light on enzymes of phenylpropanoid metabolism and hispidin biosynthesis in Polyporus hispidusBiochem. J.134(4),891-897(1973)
Zan, L.-F., Qin, J.-C., Zhang, Y.-M., et al.Antioxidant hispidin derivatives from medicinal mushroom Inonotus hispidusChem. Pharm. Bull. (Tokyo)59(6),770-772(2011)
Shao, H.J., Joeng, J.B., Kim, K.-J., et al.Anti-inflammatory activity of mushroom-derived hispidin through blocking of NF-κB activationJ. Sci. Food Agric.95(12),2482-2486(2015)
Jang, J.S., Lee, J.S., Lee, J.H., et al.Hispidin produced from Phellinus linteus protects pancreatic β-cells from damage by hydrogen peroxideArch. Pharm. Res.33(6),853-861(2010)
Gonindard, C.Synthetic hispidin, a PKC inhibitor, is more cytotoxic toward cancer cells than normal cells in vitroCell Biol. Toxicol.13(3),141-153(1997)
Park, I.-H., Jeon, S.-Y., Lee, H.-J., et al.A β-secretase (BACE1) inhibitor hispidin from the mycelial cultures of Phellinus linteusPlanta Med.70(2),143-146(2004)
