Ingenol 3,20-dibenzoate
Cat. No.：YN310240
CAS No. ：59086-90-7
| 产品名称: | Ingenol 3,20-dibenzoate |
| CAS No.: | 59086-90-7 |
| Chemical Name: | (1aR,2S,5R,5aR,6S,8aS,9R,10aR)-6-(Benzoyloxy)-4-[(benzoyloxy)methyl]-1a,2,5,5a,6,9,10,10a-octahydro-5,5a-dihydroxy-1,1,7,9-tetramethyl-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one; (+)-Ingenol 3,20-dibenzoate; Ingenol 3,20-Dibenzoate; NSC 26 |
| Synonyms: | |
| 分子量: | 556.65 |
| 分子式: | C₃₄H₃₆O₇ |
| SMILES: | O[C@]([C@H]1OC(C2=CC=CC=C2)=O)([C@@H](C(COC(C3=CC=CC=C3)=O)=C4)O)[C@]([C@@H]5C)(C=C1C)C([C@H]4[C@@](C(C)6C)([H])[C@@]6([H])C5)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ingenol 3,20-dibenzoate 是一种有效的蛋白激酶C(PKC)亚型选择性激动剂。Ingenol 3,20-dibenzoate 诱导 nPKC-delta、-epsilon 和 -theta 和 PKC-mu 从胞质部分选择性转移到颗粒组分，并通过从头合成大分子诱导形态上典型的凋亡 (apoptosis)。Ingenol 3,20-dibenzoate 可促进 NK 细胞产生 IFN-γ 和脱颗粒，尤其是当 NSCLC 细胞刺激 NK 细胞时。 |
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