Mifobate
Cat. No.：YN290005
CAS No. ：76541-72-5
规格
价格(RMB)
库存
| 产品名称: | Mifobate |
| CAS No.: | 76541-72-5 |
| Chemical Name: | phosphoric acid, (4-chlorophenyl)(dimethoxyphosphinyl)methyl dimethyl ester |
| Synonyms: | SR-202 |
| 分子量: | 358.65 |
| 分子式: | C₁₁H₁₇ClO₇P₂ |
| SMILES: | O=P(OC)(OC)OC(C1=CC=C(Cl)C=C1)P(OC)(OC)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Mifobate (SR-202) 是一种有效且特异性的PPARγ拮抗剂，可选择性的抑制噻唑烷二酮 (TZD) 诱导的 PPARγ 转录活性 (IC50=140 μM)。Mifobate 不影响 PPARα，PPARβ 或 FXR 的基础或配体刺激的转录活性。Mifobate 具有抗肥胖和抗糖尿病作用。 |
| IC50和靶点: | [{name:"PPARγ:140 μM (IC50)"}] |
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| Solvent & Solubility: |
Rieusset, J., Touri, F., Michalik, L., et al.A new selective peroxisome proliferator-activated receptor γ antagonist with antiobesity and antidiabetic activityMol. Endocrinol.16(11),2628-2644(2002)
