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Src Inhibitor 1

Cat. No.:YN440026

  • CAS No. :179248-59-0

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    • 产品名称: Src Inhibitor 1
      CAS No.: 179248-59-0
      Chemical Name: 6,7-dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine
      Synonyms:Src Kinase Inhibitor 1; Src-l1
      分子量:373.40
      分子式:C₂₂H₁₉N₃O₃
      SMILES:COC1=CC2=NC=NC(NC3=CC=C(OC4=CC=CC=C4)C=C3)=C2C=C1OC
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Src Inhibitor 1是高效选择性的双位点Src酪氨酸激酶抑制剂,对Src和Lck的IC50值分别为44 nM和88 nM。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Tian, G., Cory, M., Smith, A.A., et al.Structural determinants for potent, selective dual site inhibition of human pp60c-src by 4-anilinoquinazolinesBiochemistry40(24),7084-7091(2001)

      Bain, J., Plater, L., Elliot, M., et al.The selectivity of protein kinase inhibitors: A further updateBiochem. J.408(3),297-315(2007)

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