Src Inhibitor 1
Cat. No.:YN440026
| 产品名称: | Src Inhibitor 1 |
| CAS No.: | 179248-59-0 |
| Chemical Name: | 6,7-dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine |
| Synonyms: | Src Kinase Inhibitor 1; Src-l1 |
| 分子量: | 373.40 |
| 分子式: | C₂₂H₁₉N₃O₃ |
| SMILES: | COC1=CC2=NC=NC(NC3=CC=C(OC4=CC=CC=C4)C=C3)=C2C=C1OC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Src Inhibitor 1是高效选择性的双位点Src酪氨酸激酶抑制剂,对Src和Lck的IC50值分别为44 nM和88 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Tian, G., Cory, M., Smith, A.A., et al.Structural determinants for potent, selective dual site inhibition of human pp60c-src by 4-anilinoquinazolinesBiochemistry40(24),7084-7091(2001)
Bain, J., Plater, L., Elliot, M., et al.The selectivity of protein kinase inhibitors: A further updateBiochem. J.408(3),297-315(2007)