KX1-004
Cat. No.：YN440375
CAS No. ：518058-84-9
规格
价格(RMB)
库存
| 产品名称: | KX1-004 |
| CAS No.: | 518058-84-9 |
| Chemical Name: | 5-fluoro-N-[(3-hydroxyphenyl)methyl]-1H-indole-2-carboxamide |
| Synonyms: | KX1004,KX1 004 |
| 分子量: | 284.29 |
| 分子式: | C₁₆H₁₃FN₂O₂ |
| SMILES: | O=C(C(N1)=CC2=C1C=CC(F)=C2)NCC3=CC=CC(O)=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | KX1-004 是一种有效的，非 ATP 竞争性Src-PTK抑制剂，IC50为 40 μM。KX1-004 可以保护耳蜗免受有害噪音的影响，并防止噪音引起的听力损失 (NIHL)。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Harris, K.C., Hu, B., Hangauer, D., et al.Prevention of noise-induced hearing loss with Src-PTK inhibitorsHear Res.208(1-2),14-25(2005)
Bielefeld, E.C., Hynes, S., Pryznosch, D., et al.A comparison of the protective effects of systemic administration of a pro-glutathione drug and a Src-PTK inhibitor against noise-induced hearing lossNoise Health7(29),24-30(2005)
