UNC2541
Cat. No.:YN440217
产品名称: | UNC2541 |
CAS No.: | 1612782-86-1 |
Chemical Name: | |
Synonyms: | UNC2541; UNC-2541; UNC 2541; |
分子量: | 471.57 |
分子式: | C₂₄H₃₄FN₇O₂ |
SMILES: | O=C(C(C(NCCCC[C@@H]1N)=N2)=CN=C2NCCCCCCNC1=O)NCC3=CC=C(F)C=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | UNC2541 是一种有效 Mer 酪氨酸激酶 (MerTK) 特异性抑制剂,与 MerTK ATP 结合口袋结合,IC50值为 4.4 nM,对其选择性远高于 Axl,Tyro3 和 Flt3。UNC2541 抑制磷酸化的 MerTK (pMerTK;EC50,510 nM)。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |